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Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study

Ageing leaves characteristic traces in the DNA methylation make-up of the genome. However, the importance of DNA methylation in ageing remains unclear. The study of subtelomeric regions could give promising insights into this issue. Previously reported associations between susceptibility to age-rela...

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Detalles Bibliográficos
Autores principales: Bacalini, Maria Giulia, Reale, Anna, Malavolta, Marco, Ciccarone, Fabio, Moreno-Villanueva, María, Dollé, Martijn E. T., Jansen, Eugène, Grune, Tilman, Gonos, Efstathios S., Schön, Christiane, Bernhardt, Jürgen, Grubeck-Loebenstein, Beatrix, Sikora, Ewa, Toussaint, Olivier, Debacq-Chainiaux, Florence, Capri, Miriam, Hervonen, Antti, Hurme, Mikko, Slagboom, P. Eline, Breusing, Nicolle, Aversano, Valentina, Tagliatesta, Stefano, Franceschi, Claudio, Blasco, Maria A., Bürkle, Alexander, Caiafa, Paola, Zampieri, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190237/
https://www.ncbi.nlm.nih.gov/pubmed/33870444
http://dx.doi.org/10.1007/s11357-021-00347-9