Decreased parenchymal arteriolar tone uncouples vessel-to-neuronal communication in a mouse model of vascular cognitive impairment

Chronic hypoperfusion is a key contributor to cognitive decline and neurodegenerative conditions, but the cellular mechanisms remain ill-defined. Using a multidisciplinary approach, we sought to elucidate chronic hypoperfusion-evoked functional changes at the neurovascular unit. We used bilateral co...

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Detalles Bibliográficos
Autores principales: Kim, Ki Jung, Diaz, Juan Ramiro, Presa, Jessica L., Muller, P. Robinson, Brands, Michael W., Khan, Mohammad B., Hess, David C., Althammer, Ferdinand, Stern, Javier E., Filosa, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190257/
https://www.ncbi.nlm.nih.gov/pubmed/33410092
http://dx.doi.org/10.1007/s11357-020-00305-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190257/
https://www.ncbi.nlm.nih.gov/pubmed/33410092
http://dx.doi.org/10.1007/s11357-020-00305-x

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