Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis

In the Caenorhabditis elegans germline, thousands of mRNAs are concomitantly expressed with antisense 22G-RNAs, which are loaded into the Argonaute CSR-1. Despite their essential functions for animal fertility and embryonic development, how CSR-1 22G-RNAs are produced remains unknown. Here, we show...

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Detalles Bibliográficos
Autores principales: Singh, Meetali, Cornes, Eric, Li, Blaise, Quarato, Piergiuseppe, Bourdon, Loan, Dingli, Florent, Loew, Damarys, Proccacia, Simone, Cecere, Germano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190271/
https://www.ncbi.nlm.nih.gov/pubmed/34108460
http://dx.doi.org/10.1038/s41467-021-23615-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190271/
https://www.ncbi.nlm.nih.gov/pubmed/34108460
http://dx.doi.org/10.1038/s41467-021-23615-w

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