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Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
In the Caenorhabditis elegans germline, thousands of mRNAs are concomitantly expressed with antisense 22G-RNAs, which are loaded into the Argonaute CSR-1. Despite their essential functions for animal fertility and embryonic development, how CSR-1 22G-RNAs are produced remains unknown. Here, we show...
Autores principales: | Singh, Meetali, Cornes, Eric, Li, Blaise, Quarato, Piergiuseppe, Bourdon, Loan, Dingli, Florent, Loew, Damarys, Proccacia, Simone, Cecere, Germano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190271/ https://www.ncbi.nlm.nih.gov/pubmed/34108460 http://dx.doi.org/10.1038/s41467-021-23615-w |
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