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Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration

Zebrafish (Danio rerio) is increasingly used to assess the pharmacological activity and toxicity of compounds. The spatiotemporal distribution of seven fluorescent alkyne compounds was examined during 48 h after immersion (10 µM) or microinjection (2 mg/kg) in the pericardial cavity (PC), intraperit...

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Detalles Bibliográficos
Autores principales: Guarin, Marlly, Faelens, Ruben, Giusti, Arianna, De Croze, Noémie, Léonard, Marc, Cabooter, Deirdre, Annaert, Pieter, de Witte, Peter, Ny, Annelii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190279/
https://www.ncbi.nlm.nih.gov/pubmed/34108572
http://dx.doi.org/10.1038/s41598-021-91612-6