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Structure and mechanism of the human NHE1-CHP1 complex

Sodium/proton exchanger 1 (NHE1) is an electroneutral secondary active transporter present on the plasma membrane of most mammalian cells and plays critical roles in regulating intracellular pH and volume homeostasis. Calcineurin B-homologous protein 1 (CHP1) is an obligate binding partner that prom...

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Detalles Bibliográficos
Autores principales: Dong, Yanli, Gao, Yiwei, Ilie, Alina, Kim, DuSik, Boucher, Annie, Li, Bin, Zhang, Xuejun C., Orlowski, John, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190280/
https://www.ncbi.nlm.nih.gov/pubmed/34108458
http://dx.doi.org/10.1038/s41467-021-23496-z