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Myeloid cell-derived coagulation tissue factor is associated with renal tubular damage in mice fed an adenine diet

Patients with chronic kidney disease (CKD) commonly exhibit hypercoagulability. Increased levels of uremic toxins cause thrombogenicity by increasing tissue factor (TF) expression and activating the extrinsic coagulation cascade. TF is induced in monocytes and macrophages under pathological conditio...

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Detalles Bibliográficos
Autores principales: Yamakage, Shu, Oe, Yuji, Sato, Emiko, Okamoto, Koji, Sekimoto, Akiyo, Kumakura, Satoshi, Sato, Hiroshi, Yoshida, Mai, Nagasawa, Tasuku, Miyazaki, Mariko, Ito, Sadayoshi, Mackman, Nigel, Takahashi, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190319/
https://www.ncbi.nlm.nih.gov/pubmed/34108522
http://dx.doi.org/10.1038/s41598-021-91586-5