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Myeloid cell-derived coagulation tissue factor is associated with renal tubular damage in mice fed an adenine diet
Patients with chronic kidney disease (CKD) commonly exhibit hypercoagulability. Increased levels of uremic toxins cause thrombogenicity by increasing tissue factor (TF) expression and activating the extrinsic coagulation cascade. TF is induced in monocytes and macrophages under pathological conditio...
Autores principales: | Yamakage, Shu, Oe, Yuji, Sato, Emiko, Okamoto, Koji, Sekimoto, Akiyo, Kumakura, Satoshi, Sato, Hiroshi, Yoshida, Mai, Nagasawa, Tasuku, Miyazaki, Mariko, Ito, Sadayoshi, Mackman, Nigel, Takahashi, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190319/ https://www.ncbi.nlm.nih.gov/pubmed/34108522 http://dx.doi.org/10.1038/s41598-021-91586-5 |
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