Impact of Fas/Fasl Gene Polymorphisms on Susceptibility Risk and Imatinib Mesylate Treatment Response in Chronic Myeloid Leukaemia Patients

BACKGROUND: The FAS mediated apoptosis pathway involving the FAS and FASL genes plays a crucial role in the regulation of apoptotic cell death and imatinib mesylate (IM) mechanism of action. Promoter polymorphisms FAS-670 A>G and FAS-844 T>C which alter the transcriptional activity of these ge...

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Detalles Bibliográficos
Autores principales: Annuar, Aziati Azwari, Ankathil, Ravindran, Yunus, Nazihah Mohd, Husin, Azlan, Ab Rajab, Nur Shafawati, Abdul Aziz, Ahmad Aizat, Ibrahim, Mohd Ismail, Sulong, Sarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190357/
https://www.ncbi.nlm.nih.gov/pubmed/33639675
http://dx.doi.org/10.31557/APJCP.2021.22.2.565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190357/
https://www.ncbi.nlm.nih.gov/pubmed/33639675
http://dx.doi.org/10.31557/APJCP.2021.22.2.565

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