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Positive selection as a key player for SARS-CoV-2 pathogenicity: Insights into ORF1ab, S and E genes

The human β-coronavirus SARS-CoV-2 epidemic started in late December 2019 in Wuhan, China. It causes Covid-19 disease which has become pandemic. Each of the five-known human β-coronaviruses has four major structural proteins (E, M, N and S) and 16 non-structural proteins encoded by ORF1a and ORF1b t...

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Detalles Bibliográficos
Autores principales: Emam, Mohamed, Oweda, Mariam, Antunes, Agostinho, El-Hadidi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190378/
https://www.ncbi.nlm.nih.gov/pubmed/34118359
http://dx.doi.org/10.1016/j.virusres.2021.198472