TcpC inhibits neutrophil extracellular trap formation by enhancing ubiquitination mediated degradation of peptidylarginine deiminase 4

TcpC is a multifunctional virulence factor of uropathogenic E. coli (UPEC). Neutrophil extracellular trap formation (NETosis) is a crucial anti-infection mechanism of neutrophils. Here we show the influence of TcpC on NETosis and related mechanisms. We show NETosis in the context of a pyelonephritis...

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Detalles Bibliográficos
Autores principales: Ou, Qian, Fang, Jia-qi, Zhang, Zhe-sheng, Chi, Zhe, Fang, Jie, Xu, Di-yan, Lu, Kai-zhong, Qian, Meng-qing, Zhang, Da-yong, Guo, Jun-ping, Gao, Wei, Zhang, Na-ru, Pan, Jian-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190435/
https://www.ncbi.nlm.nih.gov/pubmed/34108482
http://dx.doi.org/10.1038/s41467-021-23881-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190435/
https://www.ncbi.nlm.nih.gov/pubmed/34108482
http://dx.doi.org/10.1038/s41467-021-23881-8

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