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A profile of brain reserve in adults at genetic risk of Alzheimer's disease

INTRODUCTION: The apolipoprotein E (APOE) ε4 allele is the greatest genetic risk factor for Alzheimer's disease (AD). Our aim was to identify the structural brain measures that mitigate the negative effect of APOE ε4 on cognition, which would have implications for AD diagnosis and treatment tri...

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Detalles Bibliográficos
Autores principales: Coughlan, Gillian, Zhukovsky, Peter, Voineskos, Aristotle, Grady, Cheryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190533/
https://www.ncbi.nlm.nih.gov/pubmed/34136636
http://dx.doi.org/10.1002/dad2.12208