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Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures

Advances in the isolation and gene expression profiling of single hematopoietic stem cells (HSCs) have permitted in-depth resolution of their molecular program. However, long-term HSCs can only be isolated to near purity from adult mouse bone marrow, thereby precluding studies of their molecular pro...

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Detalles Bibliográficos
Autores principales: Oedekoven, Caroline A., Belmonte, Miriam, Bode, Daniel, Hamey, Fiona K., Shepherd, Mairi S., Che, James Lok Chi, Boyd, Grace, McDonald, Craig, Belluschi, Serena, Diamanti, Evangelia, Bastos, Hugo P., Bridge, Katherine S., Göttgens, Berthold, Laurenti, Elisa, Kent, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190576/
https://www.ncbi.nlm.nih.gov/pubmed/33961793
http://dx.doi.org/10.1016/j.stemcr.2021.04.002