Cargando…
Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures
Advances in the isolation and gene expression profiling of single hematopoietic stem cells (HSCs) have permitted in-depth resolution of their molecular program. However, long-term HSCs can only be isolated to near purity from adult mouse bone marrow, thereby precluding studies of their molecular pro...
Autores principales: | Oedekoven, Caroline A., Belmonte, Miriam, Bode, Daniel, Hamey, Fiona K., Shepherd, Mairi S., Che, James Lok Chi, Boyd, Grace, McDonald, Craig, Belluschi, Serena, Diamanti, Evangelia, Bastos, Hugo P., Bridge, Katherine S., Göttgens, Berthold, Laurenti, Elisa, Kent, David G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190576/ https://www.ncbi.nlm.nih.gov/pubmed/33961793 http://dx.doi.org/10.1016/j.stemcr.2021.04.002 |
Ejemplares similares
-
Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations
por: Wilson, Nicola K., et al.
Publicado: (2015) -
Single‐cell molecular profiling provides a high‐resolution map of basophil and mast cell development
por: Hamey, Fiona K., et al.
Publicado: (2020) -
Machine learning predicts putative hematopoietic stem cells within large single-cell transcriptomics data sets
por: Hamey, Fiona K., et al.
Publicado: (2019) -
Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation
por: Goode, Debbie K., et al.
Publicado: (2016) -
Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells
por: Macaulay, Iain C., et al.
Publicado: (2016)