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Molecular Interactions between Two LMP2A PY Motifs of EBV and WW Domains of E3 Ubiquitin Ligase AIP4

Interactions involving Epstein–Barr virus (EBV) LMP2A and Nedd4 family E3 ubiquitin–protein ligases promote the ubiquitination of LMP2A-associated proteins, which results in the perturbation of normal B-cell signaling. Here, we solved the solution structure of the WW2 domain of hAIP4 and investigate...

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Detalles Bibliográficos
Autores principales: Seo, Min-Duk, Seok, Seung-Hyeon, Kim, Ji-Hun, Choi, Ji Woong, Park, Sung Jean, Lee, Bong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190631/
https://www.ncbi.nlm.nih.gov/pubmed/33922228
http://dx.doi.org/10.3390/life11050379