The two domains of human galectin-8 bind sialyl- and fucose-containing oligosaccharides in an independent manner. A 3D view by using NMR

The interaction of human galectin-8 and its two separate N-terminal and C-terminal carbohydrate recognition domains (CRD) to their natural ligands has been analysed using a synergistic combination of experimental NMR and ITC methods, and molecular dynamics simulations. Both domains bind the minimal...

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Detalles Bibliográficos
Autores principales: Gómez-Redondo, Marcos, Delgado, Sandra, Núñez-Franco, Reyes, Jiménez-Osés, Gonzalo, Ardá, Ana, Jiménez-Barbero, Jesús, Gimeno, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190895/
https://www.ncbi.nlm.nih.gov/pubmed/34179785
http://dx.doi.org/10.1039/d1cb00051a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190895/
https://www.ncbi.nlm.nih.gov/pubmed/34179785
http://dx.doi.org/10.1039/d1cb00051a

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