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Synthesis and immunological effects of C14-linked 4,5-epoxymorphinan analogues as novel heroin vaccine haptens

Active immunization is being explored as a potential therapeutic to combat accidental overdose and to mitigate the abuse potential of opioids. Hapten design is one of the crucial factors that determines the efficacy of a candidate vaccine to substance abuse and remains one of the most active areas o...

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Detalles Bibliográficos
Autores principales: Gutman, Eugene S., Irvin, Thomas C., Morgan, J. Brian, Barrientos, Rodell C., Torres, Oscar B., Beck, Zoltan, Matyas, Gary R., Jacobson, Arthur E., Rice, Kenner C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190897/
https://www.ncbi.nlm.nih.gov/pubmed/34179783
http://dx.doi.org/10.1039/d1cb00029b