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Synthesis and immunological effects of C14-linked 4,5-epoxymorphinan analogues as novel heroin vaccine haptens
Active immunization is being explored as a potential therapeutic to combat accidental overdose and to mitigate the abuse potential of opioids. Hapten design is one of the crucial factors that determines the efficacy of a candidate vaccine to substance abuse and remains one of the most active areas o...
Autores principales: | Gutman, Eugene S., Irvin, Thomas C., Morgan, J. Brian, Barrientos, Rodell C., Torres, Oscar B., Beck, Zoltan, Matyas, Gary R., Jacobson, Arthur E., Rice, Kenner C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190897/ https://www.ncbi.nlm.nih.gov/pubmed/34179783 http://dx.doi.org/10.1039/d1cb00029b |
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