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DNA barcode by flossing through a cylindrical nanopore

We report an accurate method to determine DNA barcodes from the dwell time measurement of protein tags (barcodes) along the DNA backbone using Brownian dynamics simulation of a model DNA and use a recursive theoretical scheme which improves the measurements to almost 100% accuracy. The heavier prote...

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Detalles Bibliográficos
Autores principales: Seth, Swarnadeep, Bhattacharya, Aniket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190898/
https://www.ncbi.nlm.nih.gov/pubmed/34178311
http://dx.doi.org/10.1039/d1ra00349f