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DNAscent v2: detecting replication forks in nanopore sequencing data with deep learning

BACKGROUND: Measuring DNA replication dynamics with high throughput and single-molecule resolution is critical for understanding both the basic biology behind how cells replicate their DNA and how DNA replication can be used as a therapeutic target for diseases like cancer. In recent years, the dete...

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Detalles Bibliográficos
Autor principal: Boemo, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191041/
https://www.ncbi.nlm.nih.gov/pubmed/34107894
http://dx.doi.org/10.1186/s12864-021-07736-6