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Zoonotic vaccinia virus strains belonging to different genetic clades exhibit immunomodulation abilities that are proportional to their virulence

BACKGROUND: The vaccinia virus (VACV) isolates, Guarani P1 virus (GP1V) and Passatempo virus (PSTV), were isolated during zoonotic outbreaks in Brazil. Each one of them belongs to two different VACV clades, defined by biological aspects that include virulence in mice and phylogenetic analysis. Consi...

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Detalles Bibliográficos
Autores principales: Lourenço, Karine Lima, Chinália, Leandro Andrade, Henriques, Lethícia Ribeiro, Rodrigues, Rodrigo Araújo Lima, da Fonseca, Flávio Guimarães
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191050/
https://www.ncbi.nlm.nih.gov/pubmed/34107993
http://dx.doi.org/10.1186/s12985-021-01595-z