Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II

Mitochondrial dysfunction is a key mechanism of cell death in hypoxic-ischemic brain injury. Neuronal pentraxin 1 (NP1) has been shown to play crucial roles in mitochondria-mediated neuronal death. However, the underlying mechanism(s) of NP1-induced mitochondrial dysfunction in hypoxia-ischemia (HI)...

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Detalles Bibliográficos
Autores principales: Al Rahim, Md, Thatipamula, Shabarish, Pasinetti, Giulio M., Hossain, Mir Ahamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191073/
https://www.ncbi.nlm.nih.gov/pubmed/34098747
http://dx.doi.org/10.1177/17590914211012888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191073/
https://www.ncbi.nlm.nih.gov/pubmed/34098747
http://dx.doi.org/10.1177/17590914211012888

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