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PPalign: optimal alignment of Potts models representing proteins with direct coupling information
BACKGROUND: To assign structural and functional annotations to the ever increasing amount of sequenced proteins, the main approach relies on sequence-based homology search methods, e.g. BLAST or the current state-of-the-art methods based on profile Hidden Markov Models, which rely on significant ali...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191105/ https://www.ncbi.nlm.nih.gov/pubmed/34112081 http://dx.doi.org/10.1186/s12859-021-04222-4 |