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PPalign: optimal alignment of Potts models representing proteins with direct coupling information

BACKGROUND: To assign structural and functional annotations to the ever increasing amount of sequenced proteins, the main approach relies on sequence-based homology search methods, e.g. BLAST or the current state-of-the-art methods based on profile Hidden Markov Models, which rely on significant ali...

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Detalles Bibliográficos
Autores principales: Talibart, Hugo, Coste, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191105/
https://www.ncbi.nlm.nih.gov/pubmed/34112081
http://dx.doi.org/10.1186/s12859-021-04222-4