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Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly
Marburg virus (MARV) is a lipid-enveloped virus harboring a negative-sense RNA genome, which has caused sporadic outbreaks of viral hemorrhagic fever in sub-Saharan Africa. MARV assembles and buds from the host cell plasma membrane where MARV matrix protein (mVP40) dimers associate with anionic lipi...
Autores principales: | Amiar, Souad, Husby, Monica L., Wijesinghe, Kaveesha J., Angel, Stephanie, Bhattarai, Nisha, Gerstman, Bernard S., Chapagain, Prem P., Li, Sheng, Stahelin, Robert V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191294/ https://www.ncbi.nlm.nih.gov/pubmed/34019871 http://dx.doi.org/10.1016/j.jbc.2021.100796 |
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