Cargando…

PIP(2) regulation of TRPC5 channel activation and desensitization

Transient receptor potential canonical type 5 (TRPC5) ion channels are expressed in the brain and kidney and have been identified as promising therapeutic targets whose selective inhibition can protect against diseases driven by a leaky kidney filter, such as focal segmental glomerular sclerosis. TR...

Descripción completa

Detalles Bibliográficos
Autores principales: Ningoo, Mehek, Plant, Leigh D., Greka, Anna, Logothetis, Diomedes E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191310/
https://www.ncbi.nlm.nih.gov/pubmed/33933453
http://dx.doi.org/10.1016/j.jbc.2021.100726