Discovery and optimization of 2-((1H-indol-3-yl)thio)-N-benzyl-acetamides as novel SARS-CoV-2 RdRp inhibitors

The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the global pandemic coronavirus disease (COVID-19), but no specific antiviral drug has been proven effective for controlling this pandemic to date. In this study, several 2-((indol-3-yl)thio)-N-benzyl-acetam...

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Detalles Bibliográficos
Autores principales: Zhang, Guo-Ning, Zhao, Jianyuan, Li, Quanjie, Wang, Minghua, Zhu, Mei, Wang, Juxian, Cen, Shan, Wang, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191315/
https://www.ncbi.nlm.nih.gov/pubmed/34147744
http://dx.doi.org/10.1016/j.ejmech.2021.113622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191315/
https://www.ncbi.nlm.nih.gov/pubmed/34147744
http://dx.doi.org/10.1016/j.ejmech.2021.113622

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