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The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II
The Cdk8 kinase module (CKM) is a dissociable part of the coactivator complex mediator, which regulates gene transcription by RNA polymerase II. The CKM has both negative and positive functions in gene transcription that remain poorly understood at the mechanistic level. In order to reconstitute the...
Autores principales: | Osman, Sara, Mohammad, Eusra, Lidschreiber, Michael, Stuetzer, Alexandra, Bazsó, Fanni Laura, Maier, Kerstin C., Urlaub, Henning, Cramer, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191332/ https://www.ncbi.nlm.nih.gov/pubmed/33933450 http://dx.doi.org/10.1016/j.jbc.2021.100734 |
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