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Calcium as a reliable marker for the quantitative assessment of endoplasmic reticulum stress in live cells

Calcium (Ca(2+)) is an essential mineral of endoplasmic reticulum (ER) luminal biochemistry because of the Ca(2+) dependence of ER-resident chaperones charged with folding de novo proteins that transit this cellular compartment. ER Ca(2+) depletion reduces the ability of chaperones to properly fold...

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Detalles Bibliográficos
Autores principales: Lebeau, Paul F., Platko, Khrystyna, Byun, Jae Hyun, Austin, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191341/
https://www.ncbi.nlm.nih.gov/pubmed/34000299
http://dx.doi.org/10.1016/j.jbc.2021.100779