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Therapeutic Induction of Tertiary Lymphoid Structures in Cancer Through Stromal Remodeling
Improving the effectiveness of anti-cancer immunotherapy remains a major clinical challenge. Cytotoxic T cell infiltration is crucial for immune-mediated tumor rejection, however, the suppressive tumor microenvironment impedes their recruitment, activation, maturation and function. Nevertheless, sol...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191417/ https://www.ncbi.nlm.nih.gov/pubmed/34122434 http://dx.doi.org/10.3389/fimmu.2021.674375 |