Cargando…

Therapeutic Induction of Tertiary Lymphoid Structures in Cancer Through Stromal Remodeling

Improving the effectiveness of anti-cancer immunotherapy remains a major clinical challenge. Cytotoxic T cell infiltration is crucial for immune-mediated tumor rejection, however, the suppressive tumor microenvironment impedes their recruitment, activation, maturation and function. Nevertheless, sol...

Descripción completa

Detalles Bibliográficos
Autores principales: Johansson-Percival, Anna, Ganss, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191417/
https://www.ncbi.nlm.nih.gov/pubmed/34122434
http://dx.doi.org/10.3389/fimmu.2021.674375