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Exocytosis by vesicle crumpling maintains apical membrane homeostasis during exocrine secretion

Exocrine secretion commonly employs micron-scale vesicles that fuse to a limited apical surface, presenting an extreme challenge for maintaining membrane homeostasis. Using Drosophila melanogaster larval salivary glands, we show that the membranes of fused vesicles undergo actomyosin-mediated foldin...

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Detalles Bibliográficos
Autores principales: Kamalesh, Kumari, Scher, Nadav, Biton, Tom, Schejter, Eyal D., Shilo, Ben-Zion, Avinoam, Ori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191493/
https://www.ncbi.nlm.nih.gov/pubmed/34102104
http://dx.doi.org/10.1016/j.devcel.2021.05.004