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Cx43 phosphorylation sites regulate pancreatic cancer metastasis

Pancreatic ductal adenocarcinoma (PDA) is aggressive, highly metastatic and characterized by a robust desmoplasia. Connexin proteins that form gap junctions have been implicated in tumor suppression for over 30 years. Cx43, the most widely expressed connexin, regulates cell behaviors, including migr...

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Detalles Bibliográficos
Autores principales: Solan, Joell L., Hingorani, Sunil R., Lampe, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191514/
https://www.ncbi.nlm.nih.gov/pubmed/33603164
http://dx.doi.org/10.1038/s41388-021-01668-x