Oocyte meiosis-coupled poly(A) polymerase α phosphorylation and activation trigger maternal mRNA translation in mice

Mammalian oocyte maturation is driven by strictly regulated polyadenylation and translational activation of maternal mRNA stored in the cytoplasm. However, the poly(A) polymerase (PAP) that directly mediates cytoplasmic polyadenylation in mammalian oocytes has not been determined. In this study, we...

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Detalles Bibliográficos
Autores principales: Jiang, Jun-Chao, Zhang, Hua, Cao, Lan-Rui, Dai, Xing-Xing, Zhao, Long-Wen, Liu, Hong-Bin, Fan, Heng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191758/
https://www.ncbi.nlm.nih.gov/pubmed/34048556
http://dx.doi.org/10.1093/nar/gkab431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191758/
https://www.ncbi.nlm.nih.gov/pubmed/34048556
http://dx.doi.org/10.1093/nar/gkab431

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