The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity

HIV-1 reverse transcription initiates at the primer binding site (PBS) in the viral genomic RNA (gRNA). Although the structure of the PBS-segment undergoes substantial rearrangement upon tRNA(Lys3) annealing, the proper folding of the PBS-segment during gRNA packaging is important as it ensures load...

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Detalles Bibliográficos
Autores principales: Song, Zhenwei, Gremminger, Thomas, Singh, Gatikrushna, Cheng, Yi, Li, Jun, Qiu, Liming, Ji, Juan, Lange, Margaret J, Zuo, Xiaobing, Chen, Shi-Jie, Zou, Xiaoqin, Boris-Lawrie, Kathleen, Heng, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191761/
https://www.ncbi.nlm.nih.gov/pubmed/33978756
http://dx.doi.org/10.1093/nar/gkab342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191761/
https://www.ncbi.nlm.nih.gov/pubmed/33978756
http://dx.doi.org/10.1093/nar/gkab342

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