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Luciferase-based reporter system for in vitro evaluation of elongation rate and processivity of ribosomes

The elongation step of translation is a key contributor to the abundance, folding and quality of proteins and to the stability of mRNA. However, control over translation elongation has not been thoroughly investigated. In this study, a Renilla–firefly luciferase fusion reporter system was further de...

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Detalles Bibliográficos
Autores principales: Kisly, Ivan, Kattel, Carolin, Remme, Jaanus, Tamm, Tiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191769/
https://www.ncbi.nlm.nih.gov/pubmed/33684199
http://dx.doi.org/10.1093/nar/gkab121