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A termination-independent role of Rat1 in cotranscriptional splicing

Rat1 is a 5′→3′ exoribonuclease in budding yeast. It is a highly conserved protein with homologs being present in fission yeast, flies, worms, mice and humans. Rat1 and its human homolog Xrn2 have been implicated in multiple nuclear processes. Here we report a novel role of Rat1 in mRNA splicing. We...

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Detalles Bibliográficos
Autores principales: Dhoondia, Zuzer, Elewa, Hesham, Malik, Marva, Arif, Zahidur, Pique-Regi, Roger, Ansari, Athar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191773/
https://www.ncbi.nlm.nih.gov/pubmed/33978753
http://dx.doi.org/10.1093/nar/gkab339