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Multiplex indexing approach for the detection of DNase I hypersensitive sites in single cells

Single cell chromatin accessibility assays reveal epigenomic variability at cis-regulatory elements among individual cells. We previously developed a single-cell DNase-seq assay (scDNase-seq) to profile accessible chromatin in a limited number of single cells. Here, we report a novel indexing strate...

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Detalles Bibliográficos
Autores principales: Gao, Weiwu, Ku, Wai Lim, Pan, Lixia, Perrie, Jonathan, Zhao, Tingting, Hu, Gangqing, Wu, Yuzhang, Zhu, Jun, Ni, Bing, Zhao, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191781/
https://www.ncbi.nlm.nih.gov/pubmed/33693880
http://dx.doi.org/10.1093/nar/gkab102