Cargando…
A structural intermediate pre-organizes the add adenine riboswitch for ligand recognition
Riboswitches are RNA sequences that regulate gene expression by undergoing structural changes upon the specific binding of cellular metabolites. Crystal structures of purine-sensing riboswitches have revealed an intricate network of interactions surrounding the ligand in the bound complex. The mecha...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191784/ https://www.ncbi.nlm.nih.gov/pubmed/33963862 http://dx.doi.org/10.1093/nar/gkab307 |