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A structural intermediate pre-organizes the add adenine riboswitch for ligand recognition

Riboswitches are RNA sequences that regulate gene expression by undergoing structural changes upon the specific binding of cellular metabolites. Crystal structures of purine-sensing riboswitches have revealed an intricate network of interactions surrounding the ligand in the bound complex. The mecha...

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Detalles Bibliográficos
Autores principales:	St-Pierre, Patrick, Shaw, Euan, Jacques, Samuel, Dalgarno, Paul A, Perez-Gonzalez, Cibran, Picard-Jean, Frédéric, Penedo, J Carlos, Lafontaine, Daniel A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191784/ https://www.ncbi.nlm.nih.gov/pubmed/33963862 http://dx.doi.org/10.1093/nar/gkab307

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