Accurate single-cell genotyping utilizing information from the local genome territory

Single-nucleotide variant (SNV) detection in the genome of single cells is affected by DNA amplification artefacts, including imbalanced alleles and early PCR errors. Existing single-cell genotyper accuracy often depends on the quality and coordination of both the target single-cell and external dat...

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Detalles Bibliográficos
Autores principales: Tu, Kailing, Lu, Keying, Zhang, Qilin, Huang, Wei, Xie, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191788/
https://www.ncbi.nlm.nih.gov/pubmed/33619552
http://dx.doi.org/10.1093/nar/gkab106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191788/
https://www.ncbi.nlm.nih.gov/pubmed/33619552
http://dx.doi.org/10.1093/nar/gkab106

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