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Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium

BACKGROUND: Anthelminthic treatment options against schistosomiasis are limited. The current treatment relies almost exclusively on a single drug, praziquantel (PZQ). As a consequence, the development of resistance to PZQ and limited activity of PZQ against earlier development stages are respectivel...

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Detalles Bibliográficos
Autores principales: Vejzagić, Nermina, Prodjinotho, Ulrich Fabien, El-Khafif, Nagwa, Huang, Ruili, Simeonov, Anton, Spangenberg, Thomas, Prazeres da Costa, Clarissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191877/
https://www.ncbi.nlm.nih.gov/pubmed/34033658
http://dx.doi.org/10.1371/journal.pntd.0009432