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Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium
BACKGROUND: Anthelminthic treatment options against schistosomiasis are limited. The current treatment relies almost exclusively on a single drug, praziquantel (PZQ). As a consequence, the development of resistance to PZQ and limited activity of PZQ against earlier development stages are respectivel...
Autores principales: | Vejzagić, Nermina, Prodjinotho, Ulrich Fabien, El-Khafif, Nagwa, Huang, Ruili, Simeonov, Anton, Spangenberg, Thomas, Prazeres da Costa, Clarissa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191877/ https://www.ncbi.nlm.nih.gov/pubmed/34033658 http://dx.doi.org/10.1371/journal.pntd.0009432 |
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