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Engineering Quick- and Long-acting Naloxone Delivery Systems for Treating Opioid Overdose

PURPOSE: Opioids have been the main factor for drug overdose deaths in the United States. Current naloxone delivery systems are effective in mitigating the opioid effects only for hours. Naloxone-loaded poly(lactide-co-glycolide) (PLGA) microparticles were prepared as quick- and long-acting naloxone...

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Detalles Bibliográficos
Autores principales: Sharifi, Farrokh, Meqbil, Yazan J., Otte, Andrew, Gutridge, Anna M., Blaine, Arryn T., van Rijn, Richard M., Park, Kinam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192039/
https://www.ncbi.nlm.nih.gov/pubmed/34114163
http://dx.doi.org/10.1007/s11095-021-03069-x