Gene-Environment Interactions in Multiple Sclerosis: A UK Biobank Study

OBJECTIVE: We sought to determine whether genetic risk modifies the effect of environmental risk factors for multiple sclerosis (MS). To test this hypothesis, we tested for statistical interaction between polygenic risk scores (PRS) capturing genetic susceptibility to MS and environmental risk facto...

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Detalles Bibliográficos
Autores principales: Jacobs, Benjamin Meir, Noyce, Alastair J., Bestwick, Jonathan, Belete, Daniel, Giovannoni, Gavin, Dobson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192056/
https://www.ncbi.nlm.nih.gov/pubmed/34049995
http://dx.doi.org/10.1212/NXI.0000000000001007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192056/
https://www.ncbi.nlm.nih.gov/pubmed/34049995
http://dx.doi.org/10.1212/NXI.0000000000001007

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