Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

RNA abundance is generally sensitive to perturbations in decay and synthesis rates, but crosstalk between RNA polymerase II transcription and cytoplasmic mRNA degradation often leads to compensatory changes in gene expression. Here, we reveal that widespread mRNA decay during early apoptosis repress...

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Detalles Bibliográficos
Autores principales: Duncan-Lewis, Christopher, Hartenian, Ella, King, Valeria, Glaunsinger, Britt A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192121/
https://www.ncbi.nlm.nih.gov/pubmed/34085923
http://dx.doi.org/10.7554/eLife.58342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192121/
https://www.ncbi.nlm.nih.gov/pubmed/34085923
http://dx.doi.org/10.7554/eLife.58342

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