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Third-Generation Anti-CD47-Specific CAR-T Cells Effectively Kill Cancer Cells and Reduce the Genes Expression in Lung Cancer Cell Metastasis

CD47 is a cell surface glycoprotein molecule, belonging to the immunoglobulin superfamily, binding to various proteins including integrins, thrombospondin-1, and signal regulatory protein α (SIRPα). CD47 is an important tumor antigen for the development and progression of various cancers. This study...

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Detalles Bibliográficos
Autores principales: La, Huyen Thi, Tran, Dao Bich Thi, Tran, Hai Manh, Nguyen, Linh Trong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192203/
https://www.ncbi.nlm.nih.gov/pubmed/34189144
http://dx.doi.org/10.1155/2021/5575260