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Association of PTPRD/PTPRT Mutation With Better Clinical Outcomes in NSCLC Patients Treated With Immune Checkpoint Blockades

The common gamma receptor–dependent cytokines and their JAK-STAT pathways play important roles in T cell immunity and have been demonstrated to be related with response to immune checkpoint blockades (ICBs). PTPRD and PTPRT are phosphatases involved in JAK-STAT pathway. However, their clinical signi...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Wu, Bingchen, Yan, Zhengqing, Wang, Guoqiang, Chen, Shiqing, Zeng, Jian, Tao, Feng, Xu, Bichun, Ke, Honggang, Li, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192300/
https://www.ncbi.nlm.nih.gov/pubmed/34123798
http://dx.doi.org/10.3389/fonc.2021.650122