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Human heart-forming organoids recapitulate early heart and foregut development

Organoid models of early tissue development have been produced for the intestine, brain, kidney and other organs, but similar approaches for the heart have been lacking. Here we generate complex, highly structured, three-dimensional heart-forming organoids (HFOs) by embedding human pluripotent stem...

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Detalles Bibliográficos
Autores principales: Drakhlis, Lika, Biswanath, Santoshi, Farr, Clara-Milena, Lupanow, Victoria, Teske, Jana, Ritzenhoff, Katharina, Franke, Annika, Manstein, Felix, Bolesani, Emiliano, Kempf, Henning, Liebscher, Simone, Schenke-Layland, Katja, Hegermann, Jan, Nolte, Lena, Meyer, Heiko, de la Roche, Jeanne, Thiemann, Stefan, Wahl-Schott, Christian, Martin, Ulrich, Zweigerdt, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192303/
https://www.ncbi.nlm.nih.gov/pubmed/33558697
http://dx.doi.org/10.1038/s41587-021-00815-9