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Human heart-forming organoids recapitulate early heart and foregut development
Organoid models of early tissue development have been produced for the intestine, brain, kidney and other organs, but similar approaches for the heart have been lacking. Here we generate complex, highly structured, three-dimensional heart-forming organoids (HFOs) by embedding human pluripotent stem...
Autores principales: | Drakhlis, Lika, Biswanath, Santoshi, Farr, Clara-Milena, Lupanow, Victoria, Teske, Jana, Ritzenhoff, Katharina, Franke, Annika, Manstein, Felix, Bolesani, Emiliano, Kempf, Henning, Liebscher, Simone, Schenke-Layland, Katja, Hegermann, Jan, Nolte, Lena, Meyer, Heiko, de la Roche, Jeanne, Thiemann, Stefan, Wahl-Schott, Christian, Martin, Ulrich, Zweigerdt, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192303/ https://www.ncbi.nlm.nih.gov/pubmed/33558697 http://dx.doi.org/10.1038/s41587-021-00815-9 |
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