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Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

BACKGROUND: Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth, preterm birth, and neonatal unit admission). We aimed to examine whether ursodeoxycholic acid affects specific adverse...

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Detalles Bibliográficos
Autores principales: Ovadia, Caroline, Sajous, Jenna, Seed, Paul T, Patel, Kajol, Williamson, Nicholas J, Attilakos, George, Azzaroli, Francesco, Bacq, Yannick, Batsry, Linoy, Broom, Kelsey, Brun-Furrer, Romana, Bull, Laura, Chambers, Jenny, Cui, Yue, Ding, Min, Dixon, Peter H, Estiú, Maria C, Gardiner, Fergus W, Geenes, Victoria, Grymowicz, Monika, Günaydin, Berrin, Hague, William M, Haslinger, Christian, Hu, Yayi, Indraccolo, Ugo, Juusela, Alexander, Kane, Stefan C, Kebapcilar, Ayse, Kebapcilar, Levent, Kohari, Katherine, Kondrackienė, Jūratė, Koster, Maria P H, Lee, Richard H, Liu, Xiaohua, Locatelli, Anna, Macias, Rocio I R, Madazli, Riza, Majewska, Agata, Maksym, Kasia, Marathe, Jessica A, Morton, Adam, Oudijk, Martijn A, Öztekin, Deniz, Peek, Michael J, Shennan, Andrew H, Tribe, Rachel M, Tripodi, Valeria, Türk Özterlemez, Naciye, Vasavan, Tharni, Wong, L F Audris, Yinon, Yoav, Zhang, Qianwen, Zloto, Keren, Marschall, Hanns-Ulrich, Thornton, Jim, Chappell, Lucy C, Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192305/
https://www.ncbi.nlm.nih.gov/pubmed/33915090
http://dx.doi.org/10.1016/S2468-1253(21)00074-1