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Myocardial salvage by succinate dehydrogenase inhibition in ischemia–reperfusion injury depends on diabetes stage in rats
Inhibition of succinate dehydrogenase (SDH) by Dimethyl Malonate (DiMal) reduces cardiac ischemia–reperfusion (IR) injury. We investigated the cardioprotective effect of DiMal in a rat model during advancing type 2 diabetes. Zucker Diabetic Fatty rats and lean controls were investigated correspondin...
Autores principales: | Tonnesen, Pernille Tilma, Hjortbak, Marie Vognstoft, Lassen, Thomas Ravn, Seefeldt, Jacob Marthinsen, Bøtker, Hans Erik, Jespersen, Nichlas Riise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8192402/ https://www.ncbi.nlm.nih.gov/pubmed/33666828 http://dx.doi.org/10.1007/s11010-021-04108-2 |
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